Collaberations, candid expressions and humble hero all present at The Molecular Mechanisms in Signal Transduction and Cancer


By Jason Williams

‘This unique advanced lecture course, Molecular Mechanisms in Signal Transduction and Cancer, brought together leaders in signal transduction research and PhD students from across the globe. The course, held in Spetses, Greece in August 2015, had an intense schedule of lectures, with researchers first going back to the basics of how they made their seminal discoveries and later describing their current research.

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Insights into platelet protein signalling from across the pond

‘My PhD project focuses on the role and regulation of the protein . Professor Wolfgang Bergmeier and his group based at the University of North Carolina in the USA have recently characterised a thrombocytopenic mouse strain (hlb mice) that has a large decrease in Rasa3 expression and is therefore a useful tool to study the function of this protein in platelets. This prompted me to arrange a visit to the Bergmeier laboratory. During this trip I generated some very useful data concerning the role of Rasa3 in ‘outside-in’ integrin signalling in platelets. An example of a microscope image from my visit showing spreading of platelets from hlb mice is shown below.

Anthony Battram

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Empowering early career researchers to speak up

By Gabriele Butkute, science policy assistant at the Biochemical Society

Members at SAS workshop
From left: Brooke Lumicisi, Jake Howden, Esther Odekunle and Emily Baldwin.

Public engagement is assessed within the Research Excellence Framework (REF) implying that is it an integral part of academic research. However, how do you divide the time between carrying out experiments at the lab bench and communicating them? And once you put yourself out there, how do you make sure that the media gets the story right? Continue reading

Peer Review: The Good, the Bad and the Ugly

By Mariana Arroja

peer review workshop“How was this paper published?” This is a question that every scientist has asked themselves at least once. Assessing specialised literature can be quite challenging, but as experience develops the easier it is to identify the bad science that is published on a daily basis. Prior to having a manuscript accepted for publication, it will have been subject to the scrutiny of a select group of scientists in a process called peer review. Despite this, poor quality research is still sometimes accepted for publication in peer reviewed journals and for some of those starting a scientific career, this reality can be, let’s say, a bit discouraging. So what exactly is happening? Is it peer review that is failing? Continue reading

The prospect of a world without antibiotics

Antibiotic resistance is one of the “biggest threats to mankind’s well-being” and at the moment a solution has not been found.

To raise awareness of this issue, the Biochemical Society and Microbiology Society organised a panel discussion entitled “Living in a world without antibiotics” at the British Science Festival 2015. In front of an audience of 75 people, Dr Lloyd Czaplewski (Director at Chemical Biology Ventures), Victoria Wells (Science Communicator at The British Society for Antimicrobial Chemotherapy) and Chair Dr Adam Roberts (Senior Lecturer in Microbial Diseases, University College London) discussed the consequences of a world without antibiotics.

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